The CU Book Store is located in the University Memorial Center (UMC) on the University of Colorado Boulder campus. The university town of Boulder is nestled at the base of the Front Range and is accessible from Denver via I-25 to US-36. CU students can easily visit the store from the Alferd Packer Grill, CU Connection arcade, meeting and club rooms, or the spectacular fountain area just north of the store's entrance.

The CU Book Store at Limelight Boulder is located at the northwest corner of campus, on the corner of Broadway and University. Parking is available in the parking garage at the northeast corner of the Limelight Boulder Hotel and Conference Center. The entrance to the CU Book Store is located off Broadway.